Comparative Genomic Analysis of Asian Haemorrhagic Septicaemia-Associated Strains of Pasteurella multocida Identifies More than 90 Haemorrhagic Septicaemia-Specific Genes

Comparative Genomic Analysis of Asian Haemorrhagic Septicaemia-Associated Strains of Pasteurella multocida Identifies More than 90 Haemorrhagic Septicaemia-Specific Genes

Pasteurella multocida is the primary causative agent of a range of economically important diseases in animals, including haemorrhagic septicaemia (HS), a rapidly fatal disease of ungulates. There is limited information available on the diversity of P. multocida strains that cause HS. Therefore, we determined draft genome sequences of ten disease-causing isolates and two vaccine strains and comp...

Analysis of Pasteurella Multocida Strains Isolated from Cattle with Haemorrhagic Septicaemia by the Use of Pfge

Forty Pasteurella multocida subsp. multocida strains collected from cattle with haemorrhagic septicaemia belonging to serotype B:2, 5 and two reference strains of serotype B:2, were examined. The strains were isolated in the years 1958 to 1962 and 1985 to 1995. Analysis of the polimorfism of restricted DNA fragments by the use of the pulsed-field gel electrophoresis (PFGE) technique of contour-...

Pathogenicity and immunogenicity of native and mutant strains of Pasteurella multocida, the causative agents of haemorrhagic septicaemia

Haemorrhagic septicaemia (HS) is a fatal systemic disease of cattle and buffaloes. Some control isachieved with administration of alum-precipitated or oil-adjuvanted killed whole-cell vaccines injectedsubcutaneously. These vaccines, however, provide only short-term immunity and for effective use, theyshould be administered annually. We constructed an aroA attenuated derivative of a Pasteurella ...

IDENTIFICATION AND Il\1MUNOGENICITY OF POLYSACCHARIDE ANTIGENS OF PASTEURELLA MULTOCIDA STRAINS INVOLVED IN HAEMORRHAGIC SEPTICAEMIA Naj1nul

Polysaccharide antigens of Pasteurella multocida serotype B:2,5 were identified by immunodiffusion and immunoelectrophoresis. The immunodiffusion tests showed that the first line, near the well containing the whole polysaccharide extract (WPE) represent LPS because this precipitation line occurs by diffusion using antiserum raised against P. multocida serotypes 8:2,5 and E:2,5 but not with 8:3,...

A biochemical and serological study of strains of Pasteurella multocida associated with haemorrhagic septicaemia in cattle and buffaloes in Srilanka